Determination of epichlorohydrin in drinking water by headspace solid-phase microextraction coupled with gas chromatography/mass spectrometry

Objective To establish a method of automatic headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography/mass spectrometry (GC/MS) for the determination of epichlorohydrin in drinking water.

Methods The 80 μm DVB/Carbon WR/PDMS was used as SPME fiber, with the condition of 250 r/min shaking, an equilibration time of 15 minutes at 35 ℃, a headspace extraction time of 15 minutes, and desorption at 250℃ for 5 minutes, and then the compound was separated by a DB-624 chromatographic column, detected by a mass spectrometer, and quantified by the external standard method.

Results Epichlorohydrin had good linearity in the range of 0.2-2.0 μg/L (r=0.999 2). This method had a detection limit of 0.03 μg/L, a quantification limit of 0.09 μg/L, a relative standard deviation of 2.2%-4.6%, and a recovery rate of 95.3%-102.8%.

Conclusion The method is simple and convenient and can be used for the determination of epichlorohydrin in drinking water.