Objective To analyze the mortality and disease burden of liver cancer in mortality surveillance areas of Jiangxi Province, China, and to provide suggestions for formulating targeted prevention and control measures against liver cancer.
Methods The data on liver cancer mortality reported in 20 national mortality surveillance areas in Jiangxi Province from 2014 to 2021 were obtained to calculate liver cancer-related crude mortality rate, age-standardized mortality rate, age-specific mortality rate, years of life lost (YLL) rate, and average years of life lost (AYLL) due to premature death, et al. The average annual percent change (AAPC) was used for analysis of trend from 2014 to 2021.
Results In mortality surveillance areas of Jiangxi Province from 2014 to 2021, the mortality rate of liver cancer was 21.41/100 000, and the age-standardized mortality rate by Chinese standard population was 20.01/100 000. The mortality rate was significantly higher in males than in females and significantly higher in rural areas than in urban areas (P < 0.05). The age-specific mortality rate of liver cancer increased with age, showing a rapid increase since 30 years old. The AAPCs in the mortality rate from 2014 to 2021 for males, females, and rural residents were 2.60%, 5.58%, and 3.55%, respectively (P < 0.05). The trends in the mortality rate of urban residents and the age-standardized mortality rate of different populations were not significant (P>0.05). The AAPCs in AYLL for males, females, urban residents, and rural residents were -1.75%, -2.88%, -2.46%, and -1.94%, respectively (P < 0.05). Female YLL rate showed an upward trend (AAPC=2.56%, P < 0.05).
Conclusion Liver cancer mortality was relatively high in Jiangxi Province, but the disease burden caused by premature death tended to decline. Males and rural residents are key populations for liver cancer prevention and control.
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