Determination of 8 nitrosamine compounds in drinking water by SPE-GC-MS

Objective To establish a method for simultaneous determination of 8 nitrosamine compounds in drinking water by solid phase extraction-gas chromatography-mass spectrometry(SPE-GC-MS).

Methods After adding internal standards, water samples were enriched, purified, and concentrated through a SPE column packed by coconut shell-derived activated carbon and determined by GC-MS, with the internal standard samples for quantification.

Results The linear range of 8 nitrosamine compounds was between 10 and 250 ng/L, with a good linear relationship (correlation coefficient r>0.998).The limit of detection was (1.26-3.00)ng/L, and the limit of determination was (4.20-10.0)ng/L. For water samples with low, medium, and high concentrations of nitrosamine compounds, the recovery rate ranged from 78.6% to 116%, and the relative standard deviation ranged from 1.50% to 11.1%. This method provided satisfactory

results for the determination of source water and terminal water.

Conclusion This method is simple, sensitive and stable, which can meet the requirements for the determination of the 8 nitrosamine compounds in drinking water and source water.