Objective To optimize the method for simultaneous analysis of 27 organic compounds in drinking water by large-volume injection programmed temperature vaporizer-gas chromatography-mass spectrometry (PTV-GC-MS).
Methods Twenty-seven organic compounds such as chlorobenzenes, organophosphorus pesticides, and organochlorine pesticides in the water were subjected to solid-phase extraction with hydrophilic-lipophilic balance cartridge, elution with ethyl acetate, detection with PTV-GC-MS, and quantification with the internal standard method.
Results The linear relationships between the 27 organic compounds were good, with all the correlation coefficients being greater than 0.995, detection limits of the method ranging from 0.007 to 0.04 μg/L, recovery rates ranging from 64.1% to 129.8%, and relative standard deviations ranging from 2.3% to 14.8% (n=6).
Conclusion The optimized method for analysis of 27 organic compounds in drinking water by PTV-GC-MS is rapid, accurate, and efficient.
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