Objectives To develop a method for simultaneous determination of 60 semi-volatile organic compounds in domestic drinking water using automatic solid phase extraction-gas chromatography-mass spectrometry (GC-MS).
Methods 5 mL methanol was added to 1 L water sample. Then the water sample was enriched by LC-Florisil SPE using automatic solid phase extraction equipment, and was eluted with 5 mL dichloromethane and 5 mL ethyl acetate, the eluent was concentrated with nitrogen to 1 mL and determined.
Results The 60 semi-volatile organic compounds showed a good linearity in the range of (0.125-4.00) μg/L, and the correlation coefficients were all more than 0.99. The method detection limits was in the range of 0.002-0.04 μg/L and the detection limits was in the range of 0.01-0.17 μg/L. The recoveries ranged from 70.8% to 129% and the relative standard deviations (RSD) ranged from 0.2% to 21.5%.
Conclusions The method has realized the automatic pretreatment which has advantages of high accuracy, simple operation and less solvent. This method was suitable for simultaneous determination of 60 semi-volatile organic compounds in domestic drinking water.
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