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    XIAOKAIYI·Yibulayin, MAYIRE·Rexiati, KANG Hong, XU Tao, JI Yuan. Toxic Effect of Soluble and Insoluble Components of PM2.5 in Urumqi City on Human Normal Lung Epithelial Cells[J]. Journal of Environmental Hygiene, 2017, 7(2): 85-89. DOI: 10.13421/j.cnki.hjwsxzz.2017.02.001
    Citation: XIAOKAIYI·Yibulayin, MAYIRE·Rexiati, KANG Hong, XU Tao, JI Yuan. Toxic Effect of Soluble and Insoluble Components of PM2.5 in Urumqi City on Human Normal Lung Epithelial Cells[J]. Journal of Environmental Hygiene, 2017, 7(2): 85-89. DOI: 10.13421/j.cnki.hjwsxzz.2017.02.001
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    Toxic Effect of Soluble and Insoluble Components of PM2.5 in Urumqi City on Human Normal Lung Epithelial Cells

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      • Abstract
    • Objective To investigate the cytotoxicity and oxidative damage of different components of atmospheric fine particulate matter (PM2.5) collected from Urumqi city on human normal lung epithelial cell (BEAS-2B).
      Method The exposure of human normal lung epithelial cells (BEAS-2B) to the soluble component and insoluble component of PM2.5 was used as an experimental model to compare the cytotoxicity of different components of PM2.5 eluted from quartz fiber filters.
      Results The cytotoxicity of soluble components was more toxic than insoluble components on BEAS-2B cells exposed to 50 μg/mL, 100 μg/mL, 200 μg/mL and 300 μg/mL PM2.5 (P < 0.01).
      Conclusion Atmospheric fine particulate matter (PM2.5) can cause cell damage, and the different composition of PM2.5 can lead to different cytotoxicity.
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