Abstract:
Selenium is an essential trace element for human.Different speciation of selenium determines its bio-availability, cancer chemoprevention and toxicological properties in human body.It is important to develop studies on analyzing the speciation of selenium in human blood and urine.An overview of recent advances and applicable methods for the speciation of selenium in human blood and urine was conducted in this paper, including preparation of samples, liquid chromatography separation and hyphenated with ICP-MS detection.The perspectives of applying HPLC-ICP-MS technique for the speciation analysis of elements are discussed.