韩京秀, 曹兆进, 刘欣燕. 室内装修污染对异常妊娠结局影响病例对照研究[J]. 环境卫生学杂志, 2013, 3(1): 1-3, 7.
    引用本文: 韩京秀, 曹兆进, 刘欣燕. 室内装修污染对异常妊娠结局影响病例对照研究[J]. 环境卫生学杂志, 2013, 3(1): 1-3, 7.
    Han Jingxiu, Cao Zhaojin, Liu Xinyan. A Case-control Study on Impact of Indoor Decoration Pollution on Abnormal Pregnancy Outcome[J]. Journal of Environmental Hygiene, 2013, 3(1): 1-3, 7.
    Citation: Han Jingxiu, Cao Zhaojin, Liu Xinyan. A Case-control Study on Impact of Indoor Decoration Pollution on Abnormal Pregnancy Outcome[J]. Journal of Environmental Hygiene, 2013, 3(1): 1-3, 7.

    室内装修污染对异常妊娠结局影响病例对照研究

    A Case-control Study on Impact of Indoor Decoration Pollution on Abnormal Pregnancy Outcome

    • 摘要:
      目的 探讨室内装修污染与异常妊娠结局之间的关系。
      方法 应用1:1匹配的病例对照研究方法, 调查在北京协和医院就诊的200名异常妊娠孕妇(病例组)及与其年龄相匹配(±2岁)的正常妊娠产妇(对照组), 应用多因素条件Logistic逐步回归进行分析。
      结果 病例组中孕期或怀孕之前半年内家中或工作单位使用有挥发性气味材料进行过装修的比例(32.0%)显著高于对照组(20.5%, χ2=6.81, P=0.009)。病例组自述有装修异味的时间(P50=3个月)显著高于对照组(P50=1个月, H=6.67, P=0.010)。以未进行过装修作为参照, 有装修异味的时间≤ 3和> 3个月的相对危险度分别为1.25和5.41(趋势性χ2=10.86, P=0.001)。在调整了其他危险因素的作用之后, 室内有装修异味的时间在3个月以上时可能显著增加孕妇发生异常妊娠的相对危险度(OR=13.36, 95%CI:1.27~140.19)。
      结论 室内装修污染可能是孕妇发生异常妊娠的危险因素, 且两者之间可能存在剂量-反应关系。

       

      Abstract:
      Objectives To study the impact of indoor decoration pollution on abnormal pregnancy.
      Methods To conduct multi-conditional logistic regression analysis based on the interview results of 200 abnormal pregnancy cases and the matched controls (age±2 years).
      Results The proportion of decoration using materials with volatile odor at home or work units during pregnancy or within six months before pregnancy in the case group (32.0%) is significantly higher than the control group (20.5%, χ2=6.81, P=0.009). The time with decoration odor in case group (P50=3 months) was significantly higher than that in the control group (P50=1 month, H=6.67, P=0.010).Taking houses without decoration odor as control, the relative risks of the time with decoration odor ≤3 and > 3 months are 1.25 and 5.41 (trend χ2=10.86, P=0.001) respectively. After adjusting the impact of other risk factors by multifactor analysis, the time with decoration odor over 3 months may significantly increase the occurrence of abnormal pregnancy (OR=13.36, 95%CI:1.27~140.19).
      Conclusion Indoor decoration pollution may be one of the risk factors for abnormal pregnancy, and a dose-response relationship may exist between them.

       

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