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    朱琳, 汪荣珊, 何柳, 赵明伍. 遵义市2011年疑似手足口病例实验室检测结果分析[J]. 环境卫生学杂志, 2012, 2(5): 237-239.
    引用本文: 朱琳, 汪荣珊, 何柳, 赵明伍. 遵义市2011年疑似手足口病例实验室检测结果分析[J]. 环境卫生学杂志, 2012, 2(5): 237-239.
    shu
    Zhu Lin, Wang Rongshan, He Liu, Zhao Mingwu. Laboratory Examination Results of Suspected Hand-Foot-and-Mouth Disease Cases in Zunyi City in 2011[J]. Journal of Environmental Hygiene, 2012, 2(5): 237-239.
    Citation: Zhu Lin, Wang Rongshan, He Liu, Zhao Mingwu. Laboratory Examination Results of Suspected Hand-Foot-and-Mouth Disease Cases in Zunyi City in 2011[J]. Journal of Environmental Hygiene, 2012, 2(5): 237-239.
    shu

    遵义市2011年疑似手足口病例实验室检测结果分析

    Laboratory Examination Results of Suspected Hand-Foot-and-Mouth Disease Cases in Zunyi City in 2011

      摘要
    • 摘要:
      目的 对贵州省遵义市2011年1 068例疑似手足口病例进行病原学监测，为手足口病的预防和控制提供科学防控依据。
      方法 对2011年全市1 068例疑似手足口病的咽拭子或肛拭子标本，进行实时荧光(Realtime-PCR)检测。
      结果 检出阳性标本668例(62.55%)，其中EV71阳性319例(47.75%)，CoxA16阳性191例(28.59%)，EV71和CoxA16两种病毒核酸阳性47例(7.04%)，其他肠道病毒阳性111例(16.62%)。发病季节主要集中在4－12月，在此期间出现两次高峰(5－9月和11－12月)，阳性标本中男女比例为(1.75: 1)，发病年龄主要集中在1~5岁儿童(97.09%)。
      结论 2011年手足口病全年均有病例发生，以1~5岁儿童为主，病原主要为EV71和CoxA16，以EV71为主，较易发展为重症。

       

      Abstract:
      Objectives To monitor the pathogens in 1 068 cases of suspected hand-foot-and-mouth disease (HFMD) in Zunyi City in 2011, to provide scientific basis for prevention and control of HFMD.
      Methods Throat swab or rectal swab specimens from 1 068 cases of suspected HFMD were tested by real-time fluorescence detection (Realtime-PCR).
      Results A total of 688 positive cases (62.25%) in 1 068 suspected HFMD cases were detected; among them, EV71 positive was detected in 319 cases (47.75%), CoxA16 positive was detected in 191 cases (28.59%), both EV71 and CoxA16 virus nucleic acid positive was detected in 47 cases (7.04%). Other intestinal virus-positive was detected in 111 cases (16.62%). The prevalent season was in April-December with two peaks (May-September and November-December). For positive samples, the ratio of male to female was 1.75: 1, the age of onset was mainly concentrated in 1~5 year-old children (97.09%).
      Conclusion The occurrence of HFMD in 2011 was mainly in April-December in children aged 1~5 years, the main pathogens were EV71 and CoxA16, the prognosis of cases with EV71-based was more severe.

       

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