沙尘暴露与结核发病关联的研究进展

    Research progress on the association between dust exposure and tuberculosis incidence

    • 摘要: 肺结核作为全球重大传染病, 其发生与传播可能受到沙尘天气这一气象事件的影响。目前对沙尘暴露与结核病之间的流行病学关联及其潜在生物学机制仍缺乏系统性的梳理与综合评述。文章阐述了沙尘天气的基本分布和理化特性, 综述了沙尘天气可导致颗粒物激增、微生物传播和空气中污染物浓度上升, 从而影响呼吸系统健康。梳理了沙尘暴影响结核病发病或发展的可能原因, 结合流行病学证据显示沙尘与肺结核发病风险存在正相关, 同时补充沙尘与肺炎等呼吸道疾病的关联研究以提供旁证。未来需进一步开展人群研究以验证该关联。

       

      Abstract: Pulmonary tuberculosis, a major global infectious disease, may be influenced in its incidence and transmission by the meteorological phenomenon of dust weather. Currently, there is a lack of systematic review and comprehensive analysis on the epidemiological association between dust exposure and tuberculosis, as well as its underlying biological mechanisms. This paper delineates the fundamental distribution and physicochemical properties of dust weather. It reviews how dust events can lead to a surge in particulate matter, facilitate microbial transmission, and increase airborne pollutant concentrations, thereby adversely affecting respiratory health. The paper synthesizes potential mechanisms through which dust storms may impact the incidence or progression of tuberculosis. Epidemiological evidence suggests a positive correlation between dust exposure and pulmonary tuberculosis risk. Furthermore, studies linking dust to other respiratory diseases, such as pneumonia, are referenced to provide supporting evidence. Future population-based studies are warranted to further validate this association.

       

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