杨琳, 吴蔚, 张雅琴, 陈晓仪, 麦麦提敏江·吾拉音, 陈欣, 王怀林, 梁倩虹, 张小鑫, 黄存瑞, 王琼. 孕期环境温度暴露与孕妇焦虑及抑郁症状的关联研究[J]. 环境卫生学杂志, 2024, 14(9): 726-735. DOI: 10.13421/j.cnki.hjwsxzz.2024.09.004
    引用本文: 杨琳, 吴蔚, 张雅琴, 陈晓仪, 麦麦提敏江·吾拉音, 陈欣, 王怀林, 梁倩虹, 张小鑫, 黄存瑞, 王琼. 孕期环境温度暴露与孕妇焦虑及抑郁症状的关联研究[J]. 环境卫生学杂志, 2024, 14(9): 726-735. DOI: 10.13421/j.cnki.hjwsxzz.2024.09.004
    YANG Lin, WU Wei, ZHANG Ya-qin, CHEN Xiao-yi, MAIMAITIMINJIANG·Wulayin, CHEN Xin, WANG Huai-lin, LIANG Qian-hong, ZHANG Xiao-xin, HUANG Cun-rui, WANG Qiong. Association of ambient temperature exposure during pregnancy with anxiety and depression symptoms in pregnant women[J]. Journal of Environmental Hygiene, 2024, 14(9): 726-735. DOI: 10.13421/j.cnki.hjwsxzz.2024.09.004
    Citation: YANG Lin, WU Wei, ZHANG Ya-qin, CHEN Xiao-yi, MAIMAITIMINJIANG·Wulayin, CHEN Xin, WANG Huai-lin, LIANG Qian-hong, ZHANG Xiao-xin, HUANG Cun-rui, WANG Qiong. Association of ambient temperature exposure during pregnancy with anxiety and depression symptoms in pregnant women[J]. Journal of Environmental Hygiene, 2024, 14(9): 726-735. DOI: 10.13421/j.cnki.hjwsxzz.2024.09.004

    孕期环境温度暴露与孕妇焦虑及抑郁症状的关联研究

    Association of ambient temperature exposure during pregnancy with anxiety and depression symptoms in pregnant women

    • 摘要:
      目的 探讨不同孕期温度和温湿度指数暴露对孕妇焦虑、抑郁的影响。
      方法 2017年6月至2020年12月在广州市番禺区妇幼保健院(何贤纪念医院)开展前瞻性队列研究。采用问卷收集孕妇基本情况, 采用焦虑自评量表(SAS)及抑郁自评量表(SDS)对孕妇进行心理评估。同时收集研究期间气象数据并计算温湿度指数, 采用多重线性回归模型和Logistic回归模型分别评估不同孕期温度及温湿度指数与SAS和SDS得分, 以及焦虑和抑郁状态的关联。
      结果 纳入研究的孕妇共5 553例, 孕早期、孕中期、孕晚期完成焦虑自评者分别为2 497、2 709、857名, 焦虑检出率分别为13.1%、8.9%、10.3%;完成抑郁自评者分别为2 554、2 784、863名, 抑郁检出率分别为27.2%、19.3%、18.9%。回归模型结果显示, 在孕中期, 调查前1周、2周、1月的环境平均温度每升高5 ℃, SAS标准分(95%CI)分别降低0.61(-1.08, -0.13)、0.70 (-1.24, -0.16)、0.75 (-1.44, -0.07)分; 焦虑发生风险OR(95%CI)分别为0.71 (0.56, 0.91)、0.61 (0.46, 0.81)、0.55 (0.38, 0.79)。以温湿度指数为暴露指标时观察到相似的结果。按调查季节分层分析发现, 冷季温度及温湿度指数升高与孕中期焦虑发生风险降低有关, 暖季温度及温湿度指数升高与抑郁发生风险降低有关。
      结论 孕期温度暴露与焦虑、抑郁症状的发生有关, 这种关联在不同季节存在差异。

       

      Abstract:
      Objective To evaluate the effects of temperature and thermal humidity index exposure on maternal anxiety and depression symptoms during pregnancy.
      Methods From June 2017 to December 2020, we conducted a prospective cohort study in the Guangzhou Panyu Maternal Child Health Hospital (Guangzhou Panyu District He Xian Memorial Hospital). A self-designed questionnaire was used to collect the demographic characteristics of pregnant women. The Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were used for psychological assessment. Daily meteorological data during the study period were collected and used to calculate the thermal humidity index (THI). A multiple linear regression model was used to evaluate the association of temperature/THI exposure with standardized SAS and SDS scores. A logistic regression model was used for assessing the association of temperature/THI exposure with maternal anxiety and depression.
      Results A total of 5 553 pregnant women were included in this study. During the first, second, and third trimesters, 2 497, 2 709, and 857 participants finished the SAS assessment, respectively. The detection rates of anxiety symptoms were 13.1%, 8.9%, and 10.3%, respectively. Moreover, 2 554, 2 784, and 863 participants finished SDS assessment and the detection rates of depressive symptoms were 27.2%, 19.3%, and 18.9%, respectively. Regression models showed that during the second trimester, with per 5 ℃ increase in average ambient temperature at one week, two weeks, and one month before the survey, the standardized SAS score (95% confidence interval CI) decreased by 0.61 (-1.08, -0.13), 0.70 (-1.24, -0.16), and 0.75 (-1.44, -0.07), respectively. The odds ratios (95%CI) for the risk of anxiety were 0.71 (0.56, 0.91), 0.61 (0.46, 0.81), and 0.55 (0.38, 0.79), respectively. Similar associations were observed with THI exposure. Stratified analysis by survey seasons revealed that higher temperatures and THI during the cold season were associated with a decreased risk of anxiety during the second trimester. While higher temperatures and THI during the warm season were linked to a reduced risk of depression.
      Conclusion Temperature exposure during pregnancy is associated with anxiety and depression symptoms, and these associations vary across seasons.

       

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