Objective To investigate the levels of the fasting plasma glucose (FPG) of employees in a railway bureau from 2015 to 2019, and to understand the situation and trend of abnormal FPG indicators in employees of different genders and ages.

Methods The FPG levels of the employees who participated in blood glucose testing from 2015 to 2019 in a railway bureau were divided into groups by year and stratified by age and gender. The distribution characteristics and change trend of hyperglycemia of employees were analyzed in the railway bureau during the 5 years. A logistic regression model was used to analyze the correlations between gender, age and their interaction with FPG levels of employees.

Results The detection rate of abnormal FPG levels was higher in males than in females(P < 0.01). The detection rate of abnormal FPG levels showed a similar trend among different age groups, which was consistent with the epidemiological survey of general population that blood glucose increasd with age, and there was a significant difference in the detection rate of abnormal FPG levels among different age groups (P < 0.01). Male and age (30-60) years old were positively associated with abnormal FPG levels, and the higher the age, the greater the risk of abnormal FPG levels(P < 0.01). However, multiplicative interaction analysis showed that the product of gender and age was not associated with abnormal FPG levels (P>0.05).

Conclusion The rate of abnormal FPG levels was higher in males than in females among the employees in the railway bureau in the five years (2015—2019), and male employees with old age were the focus of the prevention and control of diabetes.