吹扫捕集-GC-MS/MS法测定饮用水中2-甲基异莰醇和土臭素

甘平胜; 曾涛; 李晓晶; 刘苗; 杨荣; 李静; 潘心红

doi:10.13421/j.cnki.hjwsxzz.2023.12.009

吹扫捕集-GC-MS/MS法测定饮用水中2-甲基异莰醇和土臭素

Determination of 2-methylisoborneol and geosmin in drinking water by purge and trap-GC-MS/MS

摘要

摘要:
目的利用吹扫捕集-气相色谱串联质谱（GC-MS/MS）法测定生活饮用水中2-甲基异莰醇和土臭素的分析方法。
方法取5 mL水样，以高纯氮气会载气在40 mL/min流速下吹扫11 min后，热解吸进入GC-MS/MS进行分析，以2-异丁基-3-甲氧基吡嗪为内标进行定量。
结果在优化的实验条件下，2-甲基异莰醇和土臭素在5.0~100 ng/L浓度范围内线性较好，相关线性系数（R²）分别为0.999 6和0.999 8，方法检出限分别为0.13 ng/L和0.06 ng/L，水样加标回收率在92.3%~104.5%之间，相对标准偏差（RSD）为1.89%~4.07%。
结论该方法简便、快速、准确、灵敏度高，可用于测定饮用水中2-甲基异莰醇和土臭素。

Abstract:
Objective To develope a purge and trap-gas chromatography-triple quadrupole mass spectrometry(GC-MS/MS) method for determination of 2-methylisoborneol and geosmin in drinking water.
Methods After 5 mL water sample was purged with high purity nitrogen carrier gas at a flow rate of 40 mL/min for 11 min, the residue is thermally desorbed and analyzed by GC-MS/MS. The 2-isobutyl-3-methoxypyrazine was used as the internal standard for quantification Result Under the optimized experimental conditions, the linearity of 2-methylisobornol and geosmin in the concentration range of 5.0 ng/L~100 ng/L was good, with a correlation coefficient of 0.999 6 and 0.999 8, respectively. The limits of detection (LODs, S/N=3) were 0.13 ng/L for 2-methylisoborneol and 0.06 ng/L for geosmin. The recoveries ranged from 92.3% to 104.5%, and the relative standard deviations ranged 1.89% to 4.07%.
Conclusion The method is simple, rapid, accurate, and sensitive. It can be applied for the determination of 2-methylisobcamol and geosmin in drinking water.

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