季书屹, 牛贝笛, 雷浩. 新型冠状病毒通过环境传播的感染风险研究进展[J]. 环境卫生学杂志, 2023, 13(5): 310-318. DOI: 10.13421/j.cnki.hjwsxzz.2023.05.002
    引用本文: 季书屹, 牛贝笛, 雷浩. 新型冠状病毒通过环境传播的感染风险研究进展[J]. 环境卫生学杂志, 2023, 13(5): 310-318. DOI: 10.13421/j.cnki.hjwsxzz.2023.05.002
    JI Shu-yi, NIU Bei-di, LEI Hao. Research progress on the infection risk of SARS-CoV-2 by environmental transmission[J]. Journal of Environmental Hygiene, 2023, 13(5): 310-318. DOI: 10.13421/j.cnki.hjwsxzz.2023.05.002
    Citation: JI Shu-yi, NIU Bei-di, LEI Hao. Research progress on the infection risk of SARS-CoV-2 by environmental transmission[J]. Journal of Environmental Hygiene, 2023, 13(5): 310-318. DOI: 10.13421/j.cnki.hjwsxzz.2023.05.002

    新型冠状病毒通过环境传播的感染风险研究进展

    Research progress on the infection risk of SARS-CoV-2 by environmental transmission

    • 摘要:
      目的 新型冠状病毒(SARS-CoV-2)不断出现的新变异体持续引起广泛关注, 综述关于SARS-CoV-2通过环境传播的感染风险研究进展, 有助于更好地研究SARS-CoV-2的传播机制。
      方法 基于数学模型、动物模型、环境监测这三类方法, 查询国内外相关文献, 综述SARS-CoV-2通过不同路径传播的感染风险。
      结果 在符合查询条件的19 847篇中, 共计60篇纳入研究。总结数学模型的相关研究, 发现SARS-CoV-2通过飞沫传播的风险最大, 其次为气溶胶传播, 最后为接触传播。佩戴口罩和室内通风可以有效降低SARS-CoV-2的感染风险。动物模型中雪貂和仓鼠常被作为研究对象, 实验结果表明, 空气传播(包含气溶胶和飞沫传播)可致近82%的易感动物感染, 可能是SARS-CoV-2的主要传播路径。环境监测发现一些关键的物品表面可检测到SARS-CoV-2病毒, 但浓度一般较低, 使用定量微生物风险评估方法发现间接接触传播的单次感染风险可低至万分之一。
      结论 相比于间接接触传播, 空气传播可能是SARS-CoV-2的主要传播路径。

       

      Abstract:
      Objective The emerging new variants of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) continue to attract wide attention.A literature review on the infection risk of SARS-CoV-2 through environmental transmission will help understand its transmission mechanism.
      Methods Focusing on mathematical modeling, animal modeling, and environmental surveillance methods, relevant literature was searched to review the risk of SARS-CoV-2 transmission via different routes.
      Results A total of 19 847 articles met the search criteria, among which 60 studies were included in this review.Mathematical modeling studies revealed that the transmission risk of SARS-CoV-2 was the highest via droplets, followed by aerosols, and finally via contact.Wearing masks and indoor ventilation could effectively reduce the risk of SARS-CoV-2 infection.Animal experiments when ferrets and hamsters were used as research objects showed that approximately 82% of susceptible animals could be infected via airborne transmission (including aerosol and droplet transmission), which could be the major transmission route for SARS-CoV-2.According to environmental monitoring research, SARS-CoV-2 could be detected on some surfaces of critical items, generally at low concentrations, and the infection risk for a single indirect contact was estimated using quantitative microbial risk assessment to be as low as 1 in 10 000.
      Conclusion Compared with indirect contact, airborne transmission is more likely to be the main transmission route of SARS-CoV-2.

       

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