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    刘励坤, 刘婷婷, 许瑞君, 范赵钰, 李颖欣, 钟紫华, 许露曦, 丁震, 孙宏, 刘跃伟. 大气污染物短期暴露对自杀死亡风险的影响[J]. 环境卫生学杂志, 2022, 12(12): 862-869. DOI: 10.13421/j.cnki.hjwsxzz.2022.12.003
    引用本文: 刘励坤, 刘婷婷, 许瑞君, 范赵钰, 李颖欣, 钟紫华, 许露曦, 丁震, 孙宏, 刘跃伟. 大气污染物短期暴露对自杀死亡风险的影响[J]. 环境卫生学杂志, 2022, 12(12): 862-869. DOI: 10.13421/j.cnki.hjwsxzz.2022.12.003
    shu
    LIU Li-kun, LIU Ting-ting, XU Rui-jun, FAN Zhao-yu, LI Ying-xin, ZHONG Zi-hua, XU Lu-xi, DING Zhen, SUN Hong, LIU Yue-wei. Effect of short-term exposure to air pollutants on the risk of suicide mortality[J]. Journal of Environmental Hygiene, 2022, 12(12): 862-869. DOI: 10.13421/j.cnki.hjwsxzz.2022.12.003
    Citation: LIU Li-kun, LIU Ting-ting, XU Rui-jun, FAN Zhao-yu, LI Ying-xin, ZHONG Zi-hua, XU Lu-xi, DING Zhen, SUN Hong, LIU Yue-wei. Effect of short-term exposure to air pollutants on the risk of suicide mortality[J]. Journal of Environmental Hygiene, 2022, 12(12): 862-869. DOI: 10.13421/j.cnki.hjwsxzz.2022.12.003
    shu

    大气污染物短期暴露对自杀死亡风险的影响

    Effect of short-term exposure to air pollutants on the risk of suicide mortality

      摘要
    • 摘要:
      目的  定量评估大气污染物短期暴露对自杀死亡风险的影响。
      方法  基于国家死因监测系统，选取2015—2020年间江苏省24 765名因自杀死亡的居民为研究对象开展时间分层病例交叉研究。从中国高分辨率大气污染物（ChinaHighAirPollutants，CHAP）数据集提取大气污染物数据，从中国气象局陆面数据同化系统（China Meteorological Administration Land Data Assimilation System，CLDAS-V2.0）获取气象数据，基于研究对象居住地址评估其病例日和对照日大气PM2.5、PM10、SO2、NO2、CO和O3的暴露水平，采用条件Logistic回归模型分析大气污染物短期暴露与自杀死亡之间的暴露-反应关系。
      结果  2015—2020年江苏省自杀死亡人群死亡当天大气PM2.5、PM10、SO2、NO2、CO和O3的平均浓度分别为49.7 μg/m，自杀死亡的风险分别增加0.79%（95%CI：0.12%，1.46%）、0.71%（95%CI：0.25%，1.16%）、2.62%（95%CI：1.09%，4.17%）和0.51%（95%CI：0.004%，1.02%）。经双污染物模型分别调整其它污染物，NO2暴露与自杀死亡之间的关联保持稳定，而PM2.5、PM10、O3与自杀死亡的关联均减弱或消失。除暖季PM2.5与自杀死亡的关联较冷季更强外，未发现性别、年龄和季节对上述关联的效应修饰作用。
      结论  大气污染物（尤其是NO2）短期暴露与自杀死亡风险升高有关。

       

      Abstract:
      Objective  To quantitatively evaluate the effect of short-term exposure to air pollutants on the risk of suicide mortality.
      Methods  Based on the National Mortality Surveillance System, a total of 24 765 residents who died of suicide in Jiangsu Province from 2015 to 2020 were selected as the research subjects for the time-stratified case-crossover study. Air pollution data were extracted from the ChinaHighAirPollutants (CHAP) dataset. Meteorological data were obtained from the China Meteorological Administration Land Data Assimilation System (CLDAS-V2.0). The exposure levels of daily PM2.5, PM10, SO2, NO2, CO, and O3 on the case days and control days were estimated based on the residential address of participants. Conditional logistic regression models were used to analyze the exposure-response relationship between short-term exposure to air pollutants and suicide mortality.
      Results  The mean concentrations of PM2.5, PM10, SO2, NO2, CO, and O3 on the day of suicide deaths were 49.7 μg/m3, 84.5 μg/m3, 16.6 μg/m3, 34.5 μg/m3, 0.88 mg/m3, and 109.0 μg/m3, respectively, in Jiangsu Province from 2015 to 2020. The single-pollutant model result showed that PM2.5, PM10, NO2, and O3 exposure was associated with an increased risk of suicide mortality. For every 10 μg/m3 increase in exposure to PM2.5, PM10, NO2, and O3 on lag 0 day, the risk of suicide deaths increased by 0.79%95% confidence interval (CI): 0.12%-1.46%, 0.71% (95% CI: 0.25%-1.16%), 2.62% (95% CI: 1.09%-4.17%), and 0.51% (95% CI: 0.004%-1.02%), respectively. After adjustment for other air pollutants in the two-pollutant model, the association between NO2 and suicide mortality remained stable, while the association of PM2.5, PM10, and O3 with suicide mortality weakened or disappeared. No effect modification of gender, age, or season were found on the above associations, except that the association between PM2.5 and suicide mortality was stronger in warm season than that in cold season.
      Conclusion  Short-term exposure to air pollutants, especially NO2, is associated with an increased risk of suicide mortality.

       

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