固相萃取GC-MS测定饮用水中8种亚硝胺化合物

苏广宁; 钟秀华; 邓靖; 邵义娟; 方磊; 钟志雄; 余胜兵; 鲁琳; 连晓文

doi:10.13421/j.cnki.hjwsxzz.2022.01.012

固相萃取GC-MS测定饮用水中8种亚硝胺化合物

Determination of 8 nitrosamine compounds in drinking water by SPE-GC-MS

摘要

摘要:
目的建立同时测定饮用水中8种亚硝胺化合物的方法。
方法水样中加入内标物，用椰壳炭固相萃取柱进行富集、净化和浓缩，气相色谱—质谱(GC-MS)法分析，内标法定量。
结果 8种亚硝胺化合物在(10~250)ng/L的线性范围内线性关系良好(相关系数r>0.998)，方法检出限在(1.26~3.00)ng/L，定量限在(4.20~10.0)ng/L。水样低、中、高浓度亚硝胺化合物加标的回收率为78.6%~116%，相对标准偏差(RSD)在1.50%~11.1%。本方法对水源水、末梢水进行测定，结果满意。
结论本方法操作简便、灵敏度高、稳定可靠，能够满足生活饮用水及其水源水中8种亚硝胺化合物的检测要求。

Abstract:
Objective To establish a method for simultaneous determination of 8 nitrosamine compounds in drinking water by solid phase extraction-gas chromatography-mass spectrometry(SPE-GC-MS).
Methods After adding internal standards, water samples were enriched, purified, and concentrated through a SPE column packed by coconut shell-derived activated carbon and determined by GC-MS, with the internal standard samples for quantification.
Results The linear range of 8 nitrosamine compounds was between 10 and 250 ng/L, with a good linear relationship (correlation coefficient r>0.998).The limit of detection was (1.26-3.00)ng/L, and the limit of determination was (4.20-10.0)ng/L. For water samples with low, medium, and high concentrations of nitrosamine compounds, the recovery rate ranged from 78.6% to 116%, and the relative standard deviation ranged from 1.50% to 11.1%. This method provided satisfactory
results for the determination of source water and terminal water.
Conclusion This method is simple, sensitive and stable, which can meet the requirements for the determination of the 8 nitrosamine compounds in drinking water and source water.

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