Abstract: During public health emergencies, the network system of disease control and prevention agencies faces severe situations of security. To address the possible network security issues that may exist in the event of a public health emergency, disease control and prevention agencies can take related measures to strengthen the capabilities of emergency support for network security during the public health emergency, such as developing detailed responsibilities for emergency work for network security, perfecting the emergency response plan, and strengthening security inspection and training. The article discusses the network security in disease control and prevention agencies during public health emergencies.