Abstract: Though the global epidemic of COVID-19 is raging, countries around the world have put the resumption of work and production on schedule. In this article, an analysis was performed on the resumption strategies of work and production within different frameworks and on different levels in China and the United States, and comparisons were made for the differences in the current status of work resumption and the requirements for workplace and personal preventive and control between the two countries. The objective is to exchange experience in epidemic prevention and control and public health governance and to provide a reference for comprehensively coordinating epidemic prevention and control and socio-economic development with an accurate insight into epidemic changes.