哈尔滨市民经饮水和呼吸途径暴露邻苯二甲酸酯水平及健康风险评估

Daily Exposure Levels of Phthalates and Health Risk Assessment for Children and Adults in Harbin through Drinking Water and Inhalation Routes

摘要:
目的了解哈尔滨市人群对邻苯二甲酸酯（Phthalate Esters，PAEs）的暴露水平。
方法本研究采集哈尔滨市饮用水、空气PM_2.5及城市居民的血液样品，采用气质联用仪（GC/MS）7890 A-5975C分别分析三种样品中PAEs代谢物的浓度水平。
结果饮用水样品中DBP与DIBP含量显著；空气PM_2.5样品中PAEs以DEHP、DMP、DBP及DIBP为主；血样中检测出15种PAEs。儿童、青少年及成人累积暴露的危害指数（HI）分别为0.007、0.005及0.004。
结论哈尔滨市饮水和呼吸途径对PAEs的接触相对安全。

Abstract:
Objectives To understand the exposure level of Phthalate Esters(PAEs)in Harbin population through environmental media.
Methods Samples of drinking water, PM_2.5 and blood of urban residents were collected in this study and the concentration level of PAEs metabolites in these samples was analyzed by GC/MS 7 890 A-5975C.
Results The result showed that DBP and DIBP contents in water samples were significant and PM_2.5samples were mainly detected by DEHP, DMP, DBP and DIBP. 15 kinds of PAEs can be detected in blood samples. The hazard index (HI) of cumulative exposure of children, adolescents and adults were 0.007, 0.005 and 0.004 respectively.
Conclusion Harbin yesident's access to PAEs through drinking water and breathing is relatively safe.