董文坦, 丁辉, 郭群, 田霖, 王旭英, 梁凤超, 李国星, 潘小川. 复发性流产患者环境暴露评估-生物体微弱磁场检测技术应用[J]. 环境卫生学杂志, 2017, 7(2): 136-140, 145. DOI: 10.13421/j.cnki.hjwsxzz.2017.02.011
    引用本文: 董文坦, 丁辉, 郭群, 田霖, 王旭英, 梁凤超, 李国星, 潘小川. 复发性流产患者环境暴露评估-生物体微弱磁场检测技术应用[J]. 环境卫生学杂志, 2017, 7(2): 136-140, 145. DOI: 10.13421/j.cnki.hjwsxzz.2017.02.011
    DONG Wentan, DING Hui, GUO Qun, TIAN Lin, WANG Xuying, LIANG Fengchao, LI Guoxing, PAN Xiaochuan. Assessment on RSA Patients Exposure to Environmental Hazard Factors:Application of Organism Weak Magnetic Field Technology[J]. Journal of Environmental Hygiene, 2017, 7(2): 136-140, 145. DOI: 10.13421/j.cnki.hjwsxzz.2017.02.011
    Citation: DONG Wentan, DING Hui, GUO Qun, TIAN Lin, WANG Xuying, LIANG Fengchao, LI Guoxing, PAN Xiaochuan. Assessment on RSA Patients Exposure to Environmental Hazard Factors:Application of Organism Weak Magnetic Field Technology[J]. Journal of Environmental Hygiene, 2017, 7(2): 136-140, 145. DOI: 10.13421/j.cnki.hjwsxzz.2017.02.011

    复发性流产患者环境暴露评估-生物体微弱磁场检测技术应用

    Assessment on RSA Patients Exposure to Environmental Hazard Factors:Application of Organism Weak Magnetic Field Technology

    • 摘要:
      目的 探讨生物体微弱磁场检测技术在评估复发性流产(recurrent spontaneous abortion,RSA)患者暴露环境有害因素中的应用,为针对性提出预防措施提供参考依据。
      方法 晨尿样本来自2012年3月-2015年2月在北京市妇产医院确诊的828例复发性流产患者,利用生物体微弱磁场检测技术检测12项环境暴露指标(包括化学性、物理性和生物性因素)以及肝-内分泌和肾-内分泌2项健康效应指标。
      结果 复发性流产患者肝-内分泌和肾-内分泌的效应指标异常率分别为76.57%和75.36%。三组环境暴露指标异常率:化学性因素(66.30%)>生物性因素(43.72%)>物理性因素(14.13%)。不同BMI组患者之间,化学因素中的食源性指标在偏瘦患者中异常率(34.82%)高于正常体重患者(21.86%),有机化合物指标在正常体重患者中异常率(29.40%)高于超重患者(17.24%)。环境暴露指标在不同年龄组之间异常率差异无统计学意义(P>0.05)。
      结论 复发性流产患者对外环境因素尤其是化学性因素的暴露机会比较大,可能对该病发生造成影响,在生活及环境中应加强防护,减少接触,避免损伤。生物体微弱磁场检测技术能够对复发性流产患者早期暴露环境暴露指标进行相对量化的评估,可为复发性流产患者采取有针对性的干预措施提供依据。

       

      Abstract:
      Objective To explore the application of organism weak magnetic field technology in assessing the exposure of recurrent spontaneous abortion patients to environmental hazard factors, and provide reference for developing targeted preventive measures.
      Method Morning urine samples were collected from 828 female patients suffered from recurrent spontaneous abortion (RSA) to determine 12 environmental exposure indexes (chemical factors, physical factors and biological factors) and 2 exposure effect indexes (liver endocrine and kidney endocrine) by organism weak magnetic field technology in the Beijing Obstetrics and Gynecology Hospital, Capital Medical University, from March 2012 to February 2015.
      Results The exposure effect indexes of liver endocrine and kidney endocrine were prominent in all tested patients, and the abnormal rates were 76.57% and 75.36%, respectively. The abnormal rate of three environmental exposure factors were chemical factors (66.30%) > biological factors (43.72%) > physical factors (14.13%). The abnormal rate related to foodborne factors in different BMI groups was higher in the thin group than that in the normal weight group. The abnormal rate for organic compounds was higher in the normal weight group than that in the overweight group. But the difference of all indexes among five age groups were insignificant (P>0.05).
      Conclusions In general, the exposure to environmental factors, especially chemical factors, might increase the occurrence of RSA. Attention should be paid to enhancing protection, reducing exposure and avoiding damage in the environment of our daily life. The exposure of RSA patients to environmental factors could be evaluated relatively and quantitatively by organism weak magnetic field technology to provide references for the further study of developing targeted intervention.

       

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