包头市采暖期PM<sub>10</sub>中有机提取物的致突变性研究

芦静; 曲琳; 王宇梅; 贾玉巧; 高艳荣; 李琳

doi:10.13421/j.cnki.hjwsxzz.2015.05.007

包头市采暖期PM₁₀中有机提取物的致突变性研究

Mutagenicity of Organic Extracts from PM₁₀ during Heating Period in Baotou

摘要

摘要:
目的通过对包头市采暖期大气可吸入颗粒物(PM₁₀)中有机提取物的致突变性研究, 探讨包头市大气污染的危害程度。
方法于采暖期分别采集包西机务段、王府井商厦、居然苑小区、包头医学院4个功能区的PM₁₀样品, 采用Ames试验对各个功能区PM₁₀中的有机提取物进行致突变性研究。
结果 4个功能区PM₁₀中有机提取物均存在不同程度的致突变活性, 且具有较好的剂量-反应关系, 其中包西机务段、王府井商厦两点致突变性较强, 居然苑小区和包头医学院较弱。
结论包头市采暖期PM₁₀中有机提取物成分中存在具有致突变活性的物质, 提示本市大气可吸入颗粒物可能具有潜在的致癌危险性。

Abstract:
Objectives To investigate the mutagenicity of organic extracts from PM₁₀ during heating period in Baotou.
Methods PM₁₀samples were collected from 4 sampling points, including Baotou west locomotives, Wangfujing department store, Juranyuan district and Baotou medical college, during heating period; the mutagenicity of organic extracts from PM₁₀ was investigated by Ames test.
Results The mutagenicity of organic extracts from PM₁₀ was different in these four sampling points and was in a good dose-response relationship; which was stronger in Baotou west locomotives and Wangfujing department store than in Juranyuan district and Baotou medical college.
Conclusions The mutagenicity of organic extracts from PM₁₀ suggested that there was a potential carcinogenicity of polluted atmospheric particulate matter in Baotou during heating period.

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包头市采暖期PM10中有机提取物的致突变性研究

Mutagenicity of Organic Extracts from PM10 during Heating Period in Baotou

包头市采暖期PM₁₀中有机提取物的致突变性研究

Mutagenicity of Organic Extracts from PM₁₀ during Heating Period in Baotou