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儿童自闭症的环境危险因素研究 [中文引用][英文引用]

Study on Environmental Risk Factors of Children Autism Disorder

作者(英文):HUANG Danni1  JIN Yongtang1  YE Huaizhuang2  TIAN Yu1  XU Chenlu1  ZHU Ziyi3  QIU Liqian4  SHEN Jue5  XU Yingchun6 
单位(英文): 
关键词:自闭症 环境 危险因素 
关键词(英文):autism disorder  environment  risk factors 
分类号:330.57
出版年·卷·期(页码):2020·10·第3期(234-242)
DOI:
-----摘要:-------------------------------------------------------------------------------------------

目的 探索儿童自闭症与多种环境危险因素之间的关系。方法 选择特殊教育学校和康复机构的儿童为对象,共收集316名自闭症儿童和293名对照儿童的人口学、母亲孕产期和儿童生命早期的相关因素、孕期及生后的交通空气污染和父母环境接触史等信息。应用t检验、卡方检验和多因素logistic回归模型分析儿童自闭症的环境危险因素。结果 单因素分析结果显示,自闭症的发生风险与母亲产前抑郁症、母亲日常使用微波炉呈正关联,与母亲妊娠期高血压、辛辣食物的偶尔摄入呈负关联,OR(95%CI)值分别为13.52(1.63,111.93)、1.65(1.06,2.58)、0.34(0.12,0.94)、0.47(0.28,0.78)。多因素logistic回归模型分析显示,儿童自闭症与母亲产前抑郁症、日常使用微波炉呈正关联,OR(95%CI)值分别为12.05(1.46,99.48)和1.67(1.07,2.62);与母亲妊娠期高血压和辛辣食物的偶尔摄入呈负关联,OR(95%CI)值分别为0.29(0.10,0.84)和0.48(0.29,0.82)。结论 母亲产前抑郁症、日常使用微波炉可能是儿童自闭症的环境危险因素。
 

-----英文摘要:---------------------------------------------------------------------------------------

Objectives To explore the relationship between autism disorder (AD) and various environmental risk factors. Methods A total of 316 children with AD and 293 controls from some special education schools and rehabilitation institutions were recruited. Demographic information, related factors of maternal prenatal and children's early-life condition, traffic air pollution during prenatal and postnatal period, parental environmental exposure history and living habits were collected. T test, chi-square test, and multivariate logistic regression model were used to identify the risk factors for the occurrence of AD. Results Univariate analysis showed that the risk of AD was positively related to mothers' prenatal depression, mothers' daily use of microwave ovens, and negatively correlated with maternal hypertension and occasional spicy food intake, OR (95%CI) values were 13.52(1.63,111.93),1.65(1.06,2.58),0.34(0.12,0.94),0.47(0.28,0.78),respectively. Multivariate logistic analysis showed that factors positively associated with AD were maternal prenatal depression and the daily usage of microwave, OR (95%CI) values were 12.05(1.46, 99.48) and 1.67(1.07, 2.62), respectively. Factors negatively associated with AD were maternal gestational hypertension and occasional intake of spicy food, OR (95%CI) values were 0.29(0.10, 0.84) and 0.48(0.29, 0.82), respectively. Conclusions Maternal prenatal depression and daily usage of microwave may be risk factors of AD.
 

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若需在您的论文中引用此文,请按以下格式著录参考文献:
中文著录格式: 黄丹妮1,,金永堂1,,叶怀庄2,,田宇1,,徐晨露1,,祝子逸3,,邱丽倩4,,沈珏5,,徐迎春6.儿童自闭症的环境危险因素研究.环境卫生学杂志.2020;10(3):234-242.
英文著录格式: HUANG,Danni1,,JIN,Yongtang1,,YE,Huaizhuang2,,TIAN,Yu1,,XU,Chenlu1,,ZHU,Ziyi3,,QIU,Liqian4,,SHEN,Jue5,,XU,Yingchun6.Study on Environmental Risk Factors of Children Autism Disorder..2020;10(3):234-242.

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